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Ashraf Abdullah Saad


Ashraf Abdullah Saad

Sultan Qaboos University Hospital, Oman

Biography

Ashraf Abdullah Saad is a pediatric hematologist with special interest in glycoimmunology. He aims to resurrect and rejuvenate research on the potential application of complement-dependent cytotoxicity elicited by the interactions of lectins with cancer-associated glycans as powerful and pioneering armamentarium that could lead to revolution in cancer therapeutics. He introduced for the first time the concept of the lectin-protease conjugate that simulates the innate immune system mannose-binding lectin and its associated proteases (MASPs) and proposed it as pioneering cancer immunotherapy. This innovation is part of his inspirational mind trending thoughts that aim for ‘Research in fantasy until fantasy becomes a reality’.

Abstract

Abstract : The great potential of lectin-protease conjugates in cancer therapeutics